Most Recent
CTEPH Papers
Management of chronic thromboembolic pulmonary hypertension.
Wiedenroth CB, Jenkins D, Brenot P, Lang IM, Matsubara H, Pepke-Zaba J, Channick R, Jais X, Simonneau G, Delcroix M, Kerr K, de Perrot M, Mayer E, Pretorius V, Mahmud E, Poch D, Shimokawahara H, Steinberg ZL, Madani M.J Heart Lung Transplant. 2025 Jul;44(7S):S8-S14. doi: 10.1016/j.healun.2025.02.1691.PMID: 40653350 Review.
Enhancing preoperative assessment in chronic thromboembolic pulmonary hypertension: A comprehensive analysis of interobserver agreement and proximity-based CT pulmonary angiography scoring.
Grafham GK, Bambrick M, Houbois C, Mafeld S, Donahoe L, de Perrot M, McInnis MC.Heliyon. 2023 Oct 19;9(11):e20899. doi: 10.1016/j.heliyon.2023.e20899. eCollection 2023 Nov.PMID: 37954325
Impact of sex on outcome after pulmonary endarterectomy for chronic thromboembolic pulmonary hypertension.
Chan JCY, Man HSJ, Asghar UM, McRae K, Zhao Y, Donahoe LL, Wu L, Granton J, de Perrot M.J Heart Lung Transplant. 2023 Nov;42(11):1578-1586. doi: 10.1016/j.healun.2023.06.005. Epub 2023 Jul 6.PMID: 37422146
Chronic thromboembolic pulmonary hypertension secondary to a vascular malformation: case report diagnosis by lung subtraction iodine mapping.
Fawzy A, Mafeld S, Oreopoulos G, de Perrot M, McInnis MC.Front Med (Lausanne). 2023 Jun 15;10:1206116. doi: 10.3389/fmed.2023.1206116. eCollection 2023.PMID: 37396917
Balloon Pulmonary Angioplasty for Chronic Thromboembolic Pulmonary Hypertension: A Systematic Review and Meta-analysis.
Kennedy MK, Kennedy SA, Tan KT, de Perrot M, Bassett P, McInnis MC, Thenganatt J, Donahoe L, Granton J, Mafeld S.Cardiovasc Intervent Radiol. 2023 Jan;46(1):5-18. doi: 10.1007/s00270-022-03323-8. Epub 2022 Dec 6.PMID: 36474104
Pulmonary endarterectomy in severe chronic thromboembolic pulmonary hypertension: the Toronto experience.
de Perrot M, McRae K, Donahoe L, Abdelnour-Berchtold E, Thenganatt J, Granton J; Canadian CTEPH Working Group.Ann Cardiothorac Surg. 2022 Mar;11(2):133-142. doi: 10.21037/acs-2021-pte-14.PMID: 35433364
Central venoarterial extracorporeal membrane oxygenation as a bridge to recovery after pulmonary endarterectomy in patients with decompensated right heart failure.
Abdelnour-Berchtold E, Donahoe L, McRae K, Asghar U, Thenganatt J, Moric J, Cypel M, Keshavjee S, Granton J, de Perrot M.J Heart Lung Transplant. 2022 Jun;41(6):773-779. doi: 10.1016/j.healun.2022.02.022. Epub 2022 Mar 9.PMID: 35370035 Review.
Outcome after pulmonary endarterectomy for segmental chronic thromboembolic pulmonary hypertension.
de Perrot M, Donahoe L, McRae K, Thenganatt J, Moric J, Chan J, McInnis M, Jumaa K, Tan KT, Mafeld S, Granton J; Canadian CTEPH Working Group.J Thorac Cardiovasc Surg. 2022 Sep;164(3):696-707.e4. doi: 10.1016/j.jtcvs.2021.10.078. Epub 2022 Mar 1.PMID: 35361492
Pseudo Heparin Resistance After Pulmonary Endarterectomy: Role of Thrombus Production of Factor VIII.
Nykänen AI, Selby R, McRae KM, Zhao Y, Asghar UM, Donahoe L, Granton J, de Perrot M.Semin Thorac Cardiovasc Surg. 2022 Spring;34(1):315-323. doi: 10.1053/j.semtcvs.2021.03.042. Epub 2021 May 10.PMID: 33984481
Importance of computed tomography in defining segmental disease in chronic thromboembolic pulmonary hypertension.
McInnis MC, Wang D, Donahoe L, Granton J, Thenganatt J, Tan K, Kavanagh J, de Perrot M.ERJ Open Res. 2020 Dec 7;6(4):00461-2020. doi: 10.1183/23120541.00461-2020. eCollection 2020 Oct.PMID: 33313309
Symptoms Are More Useful Than Echocardiography in Patient Selection for Pulmonary Endarterectomy.
Donahoe L, Vanderlaan R, Thenganatt J, McRae K, Bykova A, Moric J, Granton J, de Perrot M. Ann Thorac Surg. 2017 Oct;104(4):1179-1185. doi: 10.1016/j.athoracsur.2017.05.024. Epub 2017 Aug 16.PMID: 28821335
Mesothelioma Papers
Characteristics of Long-term Survivors With Malignant Pleural Mesothelioma.
Opitz I, Lauk O, Werner R, Matter A, Hebeisen M, Battilana B, Batirel H, Pass H, Flores R, Wolf A, de Perrot M, Hoda MA, Klepetko W, Klikovits T, Hashimoto M, Hasegawa S, Richards WG, Bueno R.Ann Thorac Surg. 2025 Jul;120(1):108-116. doi: 10.1016/j.athoracsur.2024.10.004. Epub 2024 Oct 22.PMID: 39447855
The International Association for the Study of Lung Cancer Mesothelioma Staging Project: Proposals for Revisions of the “T” Descriptors in the Forthcoming Ninth Edition of the TNM Classification for Pleural Mesothelioma.
Gill RR, Nowak AK, Giroux DJ, Eisele M, Rosenthal A, Kindler H, Wolf A, Ripley RT, Billé A, Rice D, Opitz I, Rimner A, de Perrot M, Pass HI, Rusch VW; members of the International Association for the Study of Lung Cancer Staging and Prognostic Factors Committee, Advisory Boards and Participating Institution.J Thorac Oncol. 2024 Sep;19(9):1310-1325. doi: 10.1016/j.jtho.2024.03.007. Epub 2024 Mar 21.PMID: 38521202
JSI-124 inhibits cell proliferation and tumor growth by inducing autophagy and apoptosis in murine malignant mesothelioma.
Zhang C, Sun Q, Zhao J, Jiang N, Hao Y, Luo J, Karim S, Wu L, de Perrot M, Peng C, Zhao X.Mol Carcinog. 2023 Dec;62(12):1888-1901. doi: 10.1002/mc.23623. Epub 2023 Aug 29.PMID: 37642305
Heterogeneous RNA editing and influence of ADAR2 on mesothelioma chemoresistance and the tumor microenvironment.
Hariharan A, Qi W, Rehrauer H, Wu L, Ronner M, Wipplinger M, Kresoja-Rakic J, Sun S, Oton-Gonzalez L, Sculco M, Serre-Beinier V, Meiller C, Blanquart C, Fonteneau JF, Vrugt B, Rüschoff JH, Opitz I, Jean D, de Perrot M, Felley-Bosco E.Mol Oncol. 2022 Dec;16(22):3949-3974. doi: 10.1002/1878-0261.13322. Epub 2022 Oct 31.PMID: 36221913
Medical and Surgical Care of Patients With Mesothelioma and Their Relatives Carrying Germline BAP1 Mutations.
Carbone M, Pass HI, Ak G, Alexander HR Jr, Baas P, Baumann F, Blakely AM, Bueno R, Bzura A, Cardillo G, Churpek JE, Dianzani I, De Rienzo A, Emi M, Emri S, Felley-Bosco E, Fennell DA, Flores RM, Grosso F, Hayward NK, Hesdorffer M, Hoang CD, Johansson PA, Kindler HL, Kittaneh M, Krausz T, Mansfield A, Metintas M, Minaai M, Mutti L, Nielsen M, O’Byrne K, Opitz I, Pastorino S, Pentimalli F, de Perrot M, Pritchard A, Ripley RT, Robinson B, Rusch V, Taioli E, Takinishi Y, Tanji M, Tsao AS, Tuncer AM, Walpole S, Wolf A, Yang H, Yoshikawa Y, Zolondick A, Schrump DS, Hassan R.J Thorac Oncol. 2022 Jul;17(7):873-889. doi: 10.1016/j.jtho.2022.03.014. Epub 2022 Apr 21.PMID: 35462085
Carbon Nanotubes: A Summary of Beneficial and Dangerous Aspects of an Increasingly Popular Group of Nanomaterials.
Zhang C, Wu L, de Perrot M, Zhao X.Front Oncol. 2021 Jul 27;11:693814. doi: 10.3389/fonc.2021.693814. eCollection 2021.PMID: 34386422
A liquid biopsy for detecting circulating mesothelial precursor cells: A new biomarker for diagnosis and prognosis in mesothelioma.
Duong BTV, Wu L, Green BJ, Bavaghar-Zaeimi F, Wang Z, Labib M, Zhou Y, Cantu FJP, Jeganathan T, Popescu S, Pantea J, de Perrot M, Kelley SO.EBioMedicine. 2020 Nov;61:103031. doi: 10.1016/j.ebiom.2020.103031. Epub 2020 Oct 9.PMID: 33045471
Localized malignant mesothelioma, an unusual and poorly characterized neoplasm of serosal origin: best current evidence from the literature and the International Mesothelioma Panel.
Marchevsky AM, Khoor A, Walts AE, Nicholson AG, Zhang YZ, Roggli V, Carney J, Roden AC, Tazelaar HD, Larsen BT, LeStang N, Chirieac LR, Klebe S, Tsao MS, De Perrot M, Pierre A, Hwang DM, Hung YP, Mino-Kenudson M, Travis W, Sauter J, Beasley MB, Galateau-Sallé F.Mod Pathol. 2020 Feb;33(2):281-296. doi: 10.1038/s41379-019-0352-3. Epub 2019 Sep 4.PMID: 31485011
Malignant mesothelioma in situ: morphologic features and clinical outcome.
Churg A, Galateau-Salle F, Roden AC, Attanoos R, von der Thusen JH, Tsao MS, Chang N, De Perrot M, Dacic S.Mod Pathol. 2020 Feb;33(2):297-302. doi: 10.1038/s41379-019-0347-0. Epub 2019 Aug 2.PMID: 31375770
Association of two BRM promoter polymorphisms and smoking status with malignant pleural mesothelioma risk and prognosis.
Lee MJ, Kuehne N, Hueniken K, Liang S, Rai S, Sorotsky H, Herman M, Shepshelovich D, Bruce J, Liang M, Patel D, Cheng D, Chen Z, Eng L, Brown MC, Cho J, Leighl NB, de Perrot M, Reisman D, Xu W, Bradbury PA, Liu G.Mol Carcinog. 2019 Nov;58(11):1960-1973. doi: 10.1002/mc.23088. Epub 2019 Jul 29.PMID: 31355511
Mesothelioma: Scientific clues for prevention, diagnosis, and therapy.
Carbone M, Adusumilli PS, Alexander HR Jr, Baas P, Bardelli F, Bononi A, Bueno R, Felley-Bosco E, Galateau-Salle F, Jablons D, Mansfield AS, Minaai M, de Perrot M, Pesavento P, Rusch V, Severson DT, Taioli E, Tsao A, Woodard G, Yang H, Zauderer MG, Pass HI.CA Cancer J Clin. 2019 Sep;69(5):402-429. doi: 10.3322/caac.21572. Epub 2019 Jul 8.PMID: 31283845
Progress of malignant mesothelioma research in basic science: A review of the 14th international conference of the international mesothelioma interest group (iMig2018).
Wu L, Dell’Anno I, Lapidot M, Sekido Y, Chan ML, Kohno M, Serre-Beinier V, Felley-Bosco E, de Perrot M. Lung Cancer. 2019 Jan;127:138-145. doi: 10.1016/j.lungcan.2018.11.034. Epub 2018 Nov 29.PMID: 30642542 Review.
Curcumin induces apoptosis and inhibits angiogenesis in murine malignant mesothelioma.
Zhang C, Hao Y, Wu L, Dong X, Jiang N, Cong B, Liu J, Zhang W, Tang D, De Perrot M, Zhao X. Int J Oncol. 2018 Dec;53(6):2531-2541. doi: 10.3892/ijo.2018.4569. Epub 2018 Sep 21.PMID: 30272283
Current and Future Management of Malignant Mesothelioma: A Consensus Report from the National Cancer Institute Thoracic Malignancy Steering Committee, International Association for the Study of Lung Cancer, and Mesothelioma Applied Research Foundation.
Tsao AS, Lindwasser OW, Adjei AA, Adusumilli PS, Beyers ML, Blumenthal GM, Bueno R, Burt BM, Carbone M, Dahlberg SE, de Perrot M, Fennell DA, Friedberg J, Gill RR, Gomez DR, Harpole DH Jr, Hassan R, Hesdorffer M, Hirsch FR, Hmeljak J, Kindler HL, Korn EL, Liu G, Mansfield AS, Nowak AK, Pass HI, Peikert T, Rimner A, Robinson BWS, Rosenzweig KE, Rusch VW, Salgia R, Sepesi B, Simone CB 2nd, Sridhara R, Szlosarek P, Taioli E, Tsao MS, Yang H, Zauderer MG, Malik SM.J Thorac Oncol. 2018 Nov;13(11):1655-1667. doi: 10.1016/j.jtho.2018.08.2036. Epub 2018 Sep 25.PMID: 30266660
Scientific Advances and New Frontiers in Mesothelioma Therapeutics.
Mutti L, Peikert T, Robinson BWS, Scherpereel A, Tsao AS, de Perrot M, Woodard GA, Jablons DM, Wiens J, Hirsch FR, Yang H, Carbone M, Thomas A, Hassan R.J Thorac Oncol. 2018 Sep;13(9):1269-1283. doi: 10.1016/j.jtho.2018.06.011.PMID: 29966799
How asbestos drives the tissue towards tumors: YAP activation, macrophage and mesothelial precursor recruitment, RNA editing, and somatic mutations.
Rehrauer H, Wu L, Blum W, Pecze L, Henzi T, Serre-Beinier V, Aquino C, Vrugt B, de Perrot M, Schwaller B, Felley-Bosco E.Oncogene. 2018 May;37(20):2645-2659. doi: 10.1038/s41388-018-0153-z. Epub 2018 Mar 6.PMID: 29507420
SORORIN and PLK1 as potential therapeutic targets in malignant pleural mesothelioma.
Kato T, Lee D, Wu L, Patel P, Young AJ, Wada H, Hu HP, Ujiie H, Kaji M, Kano S, Matsuge S, Domen H, Kanno H, Hatanaka Y, Hatanaka KC, Kaga K, Matsui Y, Matsuno Y, De Perrot M, Yasufuku K.Int J Oncol. 2016 Dec;49(6):2411-2420. doi: 10.3892/ijo.2016.3765. Epub 2016 Nov 10.PMID: 27840913
The IASLC Mesothelioma Staging Project: Proposals for Revisions of the T Descriptors in the Forthcoming Eighth Edition of the TNM Classification for Pleural Mesothelioma.
Nowak AK, Chansky K, Rice DC, Pass HI, Kindler HL, Shemanski L, Billé A, Rintoul RC, Batirel HF, Thomas CF, Friedberg J, Cedres S, de Perrot M, Rusch VW; Staging and Prognostic Factors Committee, Advisory Boards and Participating Institutions.J Thorac Oncol. 2016 Dec;11(12):2089-2099. doi: 10.1016/j.jtho.2016.08.147. Epub 2016 Sep 26.PMID: 27687963
Consensus Report of the 2015 Weinman International Conference on Mesothelioma.
Carbone M, Kanodia S, Chao A, Miller A, Wali A, Weissman D, Adjei A, Baumann F, Boffetta P, Buck B, de Perrot M, Dogan AU, Gavett S, Gualtieri A, Hassan R, Hesdorffer M, Hirsch FR, Larson D, Mao W, Masten S, Pass HI, Peto J, Pira E, Steele I, Tsao A, Woodard GA, Yang H, Malik S. J Thorac Oncol. 2016 Aug;11(8):1246-1262. doi: 10.1016/j.jtho.2016.04.028.PMID: 27453164
Kinesin family members KIF11 and KIF23 as potential therapeutic targets in malignant pleural mesothelioma.
Kato T, Lee D, Wu L, Patel P, Young AJ, Wada H, Hu HP, Ujiie H, Kaji M, Kano S, Matsuge S, Domen H, Kaga K, Matsui Y, Kanno H, Hatanaka Y, Hatanaka KC, Matsuno Y, de Perrot M, Yasufuku K.Int J Oncol. 2016 Aug;49(2):448-56. doi: 10.3892/ijo.2016.3566. Epub 2016 Jun 7.PMID: 27279560
Establishment of immortalized murine mesothelial cells and a novel mesothelioma cell line.
Blum W, Pecze L, Felley-Bosco E, Worthmüller-Rodriguez J, Wu L, Vrugt B, de Perrot M, Schwaller B.In Vitro Cell Dev Biol Anim. 2015 Aug;51(7):714-21. doi: 10.1007/s11626-015-9885-z. Epub 2015 Apr 15.PMID: 25877069
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